# This is a sample input file. 
# Suggested sequence of actions: File/Read, Action/Enzymatic edges,
# Action/Reduction (slower), Action/Add pseudonodes, Action/Collapse pseudonodes
# Action/Reduction (slower), Action/Collapse degree-2 pseudonodes, 
# Action/ Reduction (faster), Transform any of these nodes into pseudonodes
# (right click on node, prepend * to node name, press Enter)
#  InsPK, InsP6, NO, NOS, PLD, PA, GPA1, OST1, pHc, Action/Collapse degree-2 pseudonodes
#
ABA -> OST1
ABA -> CaIM
ABA -> InsP6
ABA -> Ca2+c
ABA  -> NO
ABA -> InsP3
ABA -> AnionEM
ABA -> PLD 
ABA -> ROS
ABA -> GPA1
Ca2+c -| CaIM
Ca2+c -> AnionEM
InsP6 -> Ca2+c
InsP6 -> CIS
ROS -> CaIM
ROS -> Closure
ROS -| KOUT
pHc -> KOUT 
pHc  -> ROS 
PA -> Closure
PA -> ROS
NO -> Closure
NO -> AnionEM
NO -| KOUT 
ABA -> pHc
PA -> Atrboh
ABA -> PLC
NO -> CIS
InsP3 -> CIS
Ca2+c -> NOS
GPA1  -> PLD			Y
PLD -> PA			Y
InsPK  ->  InsP6		Y	E
PLC  ->  InsP3			Y	E
NOS  ->  NO			Y	E
Atrboh  ->  ROS			Y	E
CIS -> Ca2+c			Y
CaIM -> Ca2+c			Y
AnionEM -> Closure		Y
KOUT -> Closure			Y
Atrboh -> (ABA -> ROS)
Atrboh  -> (ABA -> Ca2+c)
Atrboh -> (ABA -> CaIM)
GPA1 -> (ABA -> ROS)
GPA1  -> (ABA -> AnionEM)
PLC -> (ABA -> Ca2+c)
PLC -> (ABA -> KOUT)
PLD -> (ABA -> Closure)  
NO -> (ABA -> Closure)
NO -> (ABA -> AnionEM)
NO -> (Ca2+c -> CIS)
Ca2+c -> (NO -> AnionEM)
Ca2+c -> (PLC -> InsP3)
CaIM -> (ABA -> KOUT)
InsPK -> (ABA -> AnionEM)
InsPK -> (ABA -> InsP6)
OST1 -> (ABA -> ROS)
KOUT  -> (ABA -> Closure)
ROS -> (ABA -> CaIM)